As human civilisation progresses, arts and culture have been expanding in scope and in complexity. While presenting singular form of art in a dedicated venue still goes strong for arts, more flexibility is called for in the use of space, equipment and ways of presenting contemporary arts. Moreover, artists are increasingly embracing cross-disciplinary and cross-media creations, which challenge traditional facilities designed for singular art forms. Enabling different art forms to be presented by artists and curators in a integrated approach, large-scale multi-disciplinary arts districts seem to be a solution where more room can be provided to presenting the arts with multiple options, providing even more exciting life experiences of appreciation and participation. Arts districts also offer opportunities for cultural activities and commercial events to be run complimentarily, in contrast to a clear dichotomised approach in the past. But developing and running arts districts have challenges that call for arts leaders who not only have a vision of how the space should be best used and run but also have the capability to lead, particularly when the district have to make change to address new needs. Arts leaders from different regions invited to this plenary will share their visions, thinkings and experiences.